PT  - JOURNAL ARTICLE
AU  - Lv, X.-F.
AU  - Qiu, Y.-W.
AU  - Zhang, X.-L.
AU  - Han, L.-J.
AU  - Qiu, S.-J.
AU  - Xiong, W.
AU  - Wen, G.
AU  - Zhang, Y.-Z.
AU  - Zhang, J.
TI  - Primary Intracranial Choriocarcinoma: MR Imaging Findings
AID  - 10.3174/ajnr.A2194
DP  - 2010 Nov 01
TA  - American Journal of Neuroradiology
PG  - 1994--1998
VI  - 31
IP  - 10
4099  - http://www.ajnr.org/content/31/10/1994.short
4100  - http://www.ajnr.org/content/31/10/1994.full
SO  - Am. J. Neuroradiol.2010 Nov 01; 31
AB  - SUMMARY: PICCC is the rarest, most malignant primary intracranial GCT. The purpose of this study was to describe and characterize the MR imaging findings in a series of 7 patients (6 males and 1 female; mean age, 11.9 years) with pathologically proved PICCC in our institution from 2004 to 2009. All tumors were located within the pineal (n = 6) or suprasellar (n = 1) regions. On T2-weighted MR imaging, the lesions appeared markedly heterogeneous with areas of both hypointensity and hyperintensity reflecting the histologic heterogeneity, including hemorrhage, fibrosis, cysts, or necrosis. Heterogeneous (n = 7), ringlike (n = 4), and/or intratumoral nodular (n = 3) enhancement was noted on T1-weighted images with gadolinium. These MR imaging findings, combined with patient age and serum β-HCG levels, may prove helpful in distinguishing PICCC from the more common primary brain tumors, thereby avoiding biopsy of this highly vascular tumor. GCTgerm cell tumorHCG/β-HCGhuman chorionic gonadotropin/β-human chorionic gonadotropinPICCCprimary intracranial choriocarcinoma