Table 1:

Preprocessing and features of multimodal MR imaging

Technique	Preprocessing Pipeline	Main Preprocessing Steps	Features after Preprocessing	ROI No.
T1-sMRI (volume)	Voxel-based morphometry	Denoising, bias cleaning, affine registration, segmentation, spatial normalization, volume modulation, smoothing	GM volume	166
			WM volume	166
			CSF volume	166
T1-sMRI (surface)	Surface-based morphometry	Surface reconstruction, cortical parcellation, spatial normalization, smoothing	Cortical thickness	68
			Gyrification index	68
			Fractal dimension	68
			Sulcus depth	68
Rs-fMRI	DPARSF standard preprocessing pipeline	Time point removal, section timing, realignment, affine registration, nuisance regression, head motion correction, spatial normalization, metric calculation, smoothing	fALFF	166
			Regional homogeneity	166
			DC	166
ASL	CBF quantification pipeline	Coregistration, CBF calculation, partial volume correction, spatial normalization, whole-brain normalization, smoothing	CBF	166

Note:—DPARSF indicates Data Processing Assistant for Resting-State fMRI (Matlab); sMRI, structural MR imaging.