Table 3:

Characteristics in patients with END versus without ENDa

All PatientsEND AbsentEND Present
(n = 231)(n = 205)(n = 26)P Value
Characteristics
Age (yr)70 (58–78)69 (57–78)73.5 (65–80).095
Sex, female119 (51.5)104 (50.7)15 (57.7).538
LKW to presentation 0–6 hr141 (61)128 (62.4)13 (50).286
Initial NIHSS score11 (5–18)12 (6–19)6 (3–12).005
NIHSS score at 24 hr post-MT8 (2–14)6 (2–13)18 (12–24)<.001
Use of rtPA76 (32.9)72 (35.1)4 (15.4).048
ASPECTS9 (8–10)9 (8–10)9 (8–10).663
Occlusion location.835
 LVO125 (54.1)110 (53.7)15 (57.7)
 DMVO106 (45.9)95 (46.3)11 (42.3)
LA grade 3–450 (21.6)43 (21)7 (26.9).613
CTA collateral score 0–186 (37.2)172 (35.1)14 (53.8).084
rCBF <38% (mL)17 (6–40)17 (6–45)19 (6.5–32).836
Core volume (rCBF <30% mL)8 (0–23.5)8 (0–26)6.5 (0–16).451
Tmax > 6 sec (mL)87 (50–137.5)89 (52–139)66.5 (43–116).278
Tmax > 10 sec (mL)25 (9–53)28 (11–57)18.5 (8–27).141
Mismatch volume (mL)64 (40–112.5)66 (40–113)60.5 (35–103).479
HIR ≥ 0.5448 (20.8)42 (20.5)6 (23.1).798
Pre-MT SBP (mm Hg)151.5 (137–170)151 (135–167)167.5 (146–189).010
TICI score<.001
 TICI 0–2a24 (10.4)14 (6.8)10 (38.5)
 TICI 2b–3207 (89.6)191 (93.2)16 (61.5)
No. of passes1 (1–2)1 (1–2)2 (2–4)<.001
Stroke etiology.379
 LAA28 (12.1)23 (11.2)5 (19.2)
 Cardioembolic96 (41.6)88 (42.9)8 (30.8)
 Cryptogenic103 (44.6)90 (43.9)13 (50)
 Other determined4 (1.7)4 (2)0 (0)
  • Note:—LAA indicates large artery atherosclerosis.

  • a Data are No. (%) or median (25th–75th quartile).