Pooled analyses for CTP and subparameters for detection of vasospasm and delayed cerebral ischemia
| Studies | Pooled Sensitivity (%) (95% CI) | Pooled Specificity (%) (95% CI) | Positive LR | Negative LR | Diagnostic OR | |
|---|---|---|---|---|---|---|
| Vasospasm | ||||||
| CTP | 11 | 85.6 (74.2–92.5) | 87.9 (79.2–93.3) | 7.10 (3.87–13.04) | 0.16 (0.09–0.31) | 43.41 (14.4–130.49) |
| CBF | 5 | 60.9 (45.0–74.7) | 92.2 (80.7–97.1) | 7.83 (3.06–20.06) | 0.42 (0.29–0.62) | 18.47 (6.16–55.38) |
| DCI | ||||||
| CTP | 22 | 82.1 (74.5–87.8) | 79.6 (73.0–84.9) | 4.01 (2.94–5.47) | 0.23 (0.12–0.33) | 17.79 (9.66–32.76) |
| CBF | 12 | 73.5 (62.0–82.4) | 84.1 (77.1–89.3) | 4.62 (3.12–6.84) | 0.31 (0.32–0.47) | 14.64 (7.58–28.25) |
| CBV | 7 | 64.3 (50.6–75.9) | 73.9 (60.1–84.1) | 2.46 (1.72–3.52) | 0.48 (0.37–0.64) | 5.08 (3.16–8.17) |
| MTT | 12 | 80.7 (73.3–86.5) | 69.3 (61.4–76.2) | 2.63 (2.04–3.39) | 0.28 (0.20–0.40) | 9.46 (5.49–16.29) |
| TTP | 7 | 82.2 (71.4–89.5) | 70.6 (59.2–79.9) | 2.79 (1.91–4.09) | 0.25 (0.15–0.43) | 11.06 (4.85–25.20) |
| Tmax | 4 | 63.8 (52.5–73.8) | 81.5 (72.5–88.1) | 3.45 (2.44–4.88) | 0.44 (0.34–0.57) | 7.77 (5.00–12.09) |