Baseline Characteristics of the MR Study Group
| Baseline Characteristics | Control Group (n = 28) | AD Group (n = 28) | P value* |
|---|---|---|---|
| Sociodemographics and anthropometrics | |||
| Mean age at observation ± SD (y) | 69 ± 8 | 74 ± 9 | .05 |
| (range) | (54–83) | (53–86) | |
| Women | 19 (68%) | 22 (79%) | NS |
| Mean education ± SD (y) | 8 ± 3 | 7 ± 4 | NS |
| (range) | (5–19) | (2–18) | |
| Dementia-related variables | |||
| MMSE score ± SD | 29.2 ± 1.5 | 20.5 ± 4.2 | <.0001 |
| (range) | (25–30) | (12–27) | |
| CDR 0/.5/1/2 or 3 | 28/0/0/0 | 0/8/12/8 | <.0001 |
| Mean disease duration ± SD (mo) | — | 42 ± 26 | — |
| (range) | (9–120) | ||
| ApoE ε4 allele† | 6/52 (12%) | 17/52 (33%) | .02 |
* t test for independent samples or chi-square test.
† Genotyping available for 26 patients with AD and 26 control subjects.