Fractional anisotropy and mean diffusivity at different anatomic sites in nine medulloblastoma survivors (patients) and age-matched controls
| Fractional anisotropy (FA) | Mean Diffusivity (MD) | |||||||
|---|---|---|---|---|---|---|---|---|
| Patient (SD) | Control (SD) | Δ (%) | P Value | Patient (SD) | Control (SD) | Δ (%) | P Value | |
| Pons | 0.30 (0.04) | 0.35 (0.02) | −12.4 | 0.004* | 1.11 (0.14) | 1.14 (0.05) | −2.8 | 0.422 |
| Cereb | 0.15 (0.03) | 0.17 (0.04) | −15.7 | 0.042† | 1.37 (0.25) | 1.09 (0.04) | 25.9 | 0.010† |
| Medulla | 0.31 (0.06) | 0.36 (0.06) | −15.7 | 0.030† | 1.28 (0.21) | 1.17 (0.13) | 9.3 | 0.270 |
| FWM | 0.24 (0.08) | 0.30 (0.06) | −18.4 | 0.079 | 1.30 (0.15) | 1.22 (0.06) | 6.7 | 0.066 |
| PWM | 0.33 (0.07) | 0.41 (0.05) | −19 | 0.028† | 1.24 (0.10) | 1.17 (0.08) | 5.7 | 0.090 |
| CR | 0.38 (0.10) | 0.47 (0.10) | −17.9 | 0.008* | 0.95 (0.12) | 0.92 (0.12) | 7.1 | 0.300 |
Note.—Cereb indicates cerebellar hemisphere; FWM, frontal white matter; PWM, parietal white matter; and CR, corona radiata.
Δ (%) = Percentage of reduction in FA of patients compared with controls.
* P < .01
† P < .05.