Clinical characteristics, neuropsychiatric symptoms, and radiologic abnormalities of 11 patients with a history of NPSLE
| Patient No./Age/Sex | MR Imaging Abnormalities | Mean WML size, mm | NP Symptoms and Time Since Occurrence* |
|---|---|---|---|
| 1/47 y/F | 2 WMLs | 5 ±0 | Cerebrovascular disease,† 3 mo |
| 2/6 mo/F | Small cerebellar infarction, cerebral atrophy, 2 WMLs | 6 ± 1.4 | Primary generalized tonic-clonic seizures, 6 mo |
| 3/41 y/F | 7 WMLs | 3.7 ± 2.0 | Movement disorder, 18 mo |
| 4/25 y/F | 6 WMLs, cerebral atrophy | 3.7 ± 1.0 | Absence seizures, 10 mo |
| 5/27 y/F | No WML | NA | Cerebrovascular disease,† 10 mo |
| 6/36 y/F | No WML | NA | Cerebrovascular Disease,† 6 mo |
| 7/49 y/F | 21 WML | 3.0 ± 1.1 | Cranial neuropathy, 2 mo |
| 8/32 y/F | Cerebral trophy, 29 WMLs | 6.3 ± 3.9 | Cerebrovascular disease,† cognitive dysfunction, 5 mo |
| 9/26 y/F | No WML | NA | Acute confusional state, 10 mo |
| 10/24 y/F | Small venous angioma, left frontal | NA | Absence seizures, 7 mo |
| 11/39 y/F | No WML | NA | Headache from intracranial hypertension, 5 mo |
Note.—WML indicates white matter lesion.
* According to the American College of Rheumatology nomenclature and case definitions for NPSLE.
† No infarctions present on MR images obtained at the time of manifestation.