TABLE 3:

Brain single-voxel 1H MR spectroscopy of the patients presented in Table 1 (STEAM sequence at echo-time of 30 ms)

Patient No.CerebellumWhite MatterParieto-occipital Cortex
mlChoNAALac0.9 ppmmIChoNAALac0.9 ppmmIChoNAALac0.9 ppm
10.50.871.090.230.630.801.330.520.551.190.25
20.620.981.060.270.711.171.340.620.761.32
30.750.731.010.250.620.821.330.320.530.721.34
40.780.610.920.801.151.320.530.551.16
50.870.941.150.320.721.011.360.690.611.180.33
60.580.901.020.450.691.191.210.480.670.521.37
70.590.890.950.710.961.370.560.521.14
80.570.901.090.290.641.031.290.640.771.320.25
90.690.820.840.300.751.131.370.710.591.180.37
100.550.871.050.640.931.470.420.550.631.41
110.610.861.090.71.11.30.350.510.651.160.51
120.670.660.970.210.670.831.380.520.721.29
130.640.940.830.751.141.530.640.741.190.22
140.670.820.990.240.260.741.291.310.450.290.760.641.220.390.25
150.600.750.660.310.210.630.941.310.290.210.770.771.220.420.22
Normals
Mean ± SD0.65 ± 0.090.96 ± 0.061.19 ± 0.050.67 ± 0.071.19 ± 0.061.36 ± 0.040.64 ± 0.040.76 ± 0.061.41 ± 0.06
  • Note.—Metabolites’ resonance intensities are expressed as ratios to the Creatine/Phosphocreatine (Cr, at 3.05 ppm) signal intensities.

  • mI = myoinositol, at 3.56 ppm; Cho = choline, at 3.05 ppm; NAA = N-acetyl aspartate, at 2.01 ppm; Lac = lactate, at 1.33 ppm. The signal at 0.9 ppm could be either related to lipids or to branched chain amino acids.