TABLE 1:

Clinical characteristics and therapeutic regimens

Patient No./Age (y)/SexBrain TumorSurgeryRadiotherapy (dose/Fx)Chemotherapy
1/70/MMalignant lymphomaBiopsy40 Gy WB with 14 Gy boost/22 FxMTX
2/53/FMalignant lymphomaNone40 Gy WB with 14 Gy boost/28 FxMTX, ICE
3/55/FMetastatic tumor (pulmonary adenocarcinoma)Total removal30 Gy WB/10 FxNone
4/53/MGlioblastomaPartial removal30 Gy WB/15 FxCE, other
5/64/MMetastatic tumor (pulmonary adenocarcinoma)Total removal30 Gy WB with 15 Gy boost (stereotactic radiosurgery)/11 FxNone
6/61/FMalignant lymphomaBiopsy30 Gy WB/14 FxMTX, ICE, other*
7/21/MMedulloblastomaPartial removal32 Gy WB with 22 Gy boost/22 FxICE, CE
8/26/MPineal germinomaBiopsy30 Gy WB with 20 Gy boost/20 FxCE
  • Note.—WB indicates whole brain; Fx, fraction; MTX, methotrexate; ICE, ifosfamide, carboplatin, and etoposide; CE, carboplatin and etoposide; other, other chemotherapy (nimustine, vincristine, procarbazine); other

  • * , intrathecal chemotherapy (rituximab).