Correlation coefficient signs between R2 values and neuropsychological test scores for the 12 subjects with memory complaints
Region | Hemisphere | MMSE | CVLT IFR | CVLT SDFR | CVLT LDFR |
---|---|---|---|---|---|
Gray matter | |||||
Globus pallidus | L | + | + | − | − |
R | + | − | − | − | |
Putamen | L | − | − | − | − |
R | − | − | − | − | |
Caudate nucleus | L | − | − | − | − |
R | − | − | − | − | |
Frontal cortex | L | + | − | − | − |
R | − | − | − | + | |
Temporal cortex | L | + | − | − | − |
R | − | − | − | − | |
Hippocampus | L | + | + | + | − |
R | − | − | − | − | |
Thalamus | L | − | − | − | − |
R | − | − | − | − | |
Red nucleus | L | − | − | − | − |
R | − | − | − | − | |
Substantia nigra | L | − | − | − | − |
R | − | − | − | − | |
White matter | |||||
Corpus callosum | L | + | + | + | + |
R | + | + | + | − | |
Subcortical frontal white | L | + | + | + | + |
R | + | + | + | + | |
Internal capsule | L | − | + | − | − |
R | − | − | − | + | |
Frontal white | L | + | + | + | + |
R | + | + | + | + | |
Temporal white | L | + | + | + | + |
R | − | − | − | − |
Note.— CVLT indicates California Verbal Learning Test; IFR, immediate free recall; LDFR, long delay free recall; MMSE, Mini Mental State Examination; SDFR, short delay free recall. Data are displayed as the revelant Spearman’s rank-order partial correlation coefficient sign (+, positive; −, negative) for each brain region and test score. Note the overall frequency of negative correlation coefficients for gray matter regions and positive correlation coefficients for white matter regions.