Statistics for quantitative hippocampal MR imaging data (HADC, HCVOL, HCT2, and HCSI)
Hippocampus | Controls (n = 20) | Right TLE (n = 29) | Left TLE (n = 26) |
---|---|---|---|
ADC (mm2/s 105) (HADC) | |||
Right hippocampus | 0.87 ± 0.03 (0.83–0.93) | 1.03 ± 0.14 (0.83–1.34)†§ | 0.86 ± 0.05 (0.83–0.96) |
Left hippocampus | 0.88 ± 0.03 (0.84–0.93) | 0.85 ± 0.06 (0.76–1.04) | 1.01 ± 0.15 (0.80–1.39)†§ |
A.I. | 1.3 ± 1.2 (0.02–3.9) | 17.6 ± 10.8 (2.7–44.7)§ | 15.2 ± 12.5 (0.3–38.5)§ |
Volume (mm3) (HCVOL) | |||
Right hippocampus | 3611 ± 350 (3050–4450)§ | 2591 ± 587 (1449–3843)†§ | 3354 ± 399 (2251–3947)‡ |
Left hippocampus | 3488 ± 320 (3077–4246) | 3434 ± 400 (2295–4118) | 2427 ± 763 (1218–3660)†§ |
A.I. | 3.8 ± 2.2 (0.8–7.5) | 30.9 ± 17.2 (4.1–77.8)‡ | 36.1 ± 24.0 (0.2–78.7)§ |
T2 (ms) (HCT2) | |||
Right hippocampus | 83.1 ± 2.3 (78.7–86.3) | 92.8 ± 5.7 (80.8–109)†§ | 85.0 ± 4.1 (72.6–92.4) |
Left hippocampus | 82.6 ± 2.8 (78.1–87.0) | 85.3 ± 3.2 (78.9–93.2)‡ | 93.2 ± 7.3 (79.8–110.3)†§ |
A.I. | 1.7 ± 1.0 (0.5–3.5) | 9.2 ± 5.0 (0.8–24.9)§ | 9.6 ± 7.9 (0.6–27.7)§ |
NAA/(Cho + CRE) (ppm) (HCSI) | |||
Right hippocampus | 0.79 ± 0.05 (0.72–0.92) | 0.56 ± 0.12 (0.33–0.79)†§ | 0.64 ± 0.14 (0.46–1.03)§ |
Left hippocampus | 0.78 ± 0.06 (0.66–0.87) | 0.64 ± 0.08 (0.42–0.81)§ | 0.52 ± 0.11 (0.37–0.76)†§ |
A.I. | 3.5 ± 3.1 (0.11–11.2) | 16.9 ± 17.3 (1.6–62.0)§ | 21.4 ± 12.0 (0.9–39.3)§ |
Note:—TLE indicates temporal lobe epilepsy; ADC, apparent diffusion coefficient; A.I., asymmetry index; NAA/(Cho + Cre), N-acetyl-aspartate to choline and creatine ratio, or HCSI. All values are expressed as mean ± 1 SD (range).
*Significantly different from the contralateral side at α level of .05.
† Significantly different from the contralateral side at α level of .01.
‡ Significantly different from the correspondent control side at α level of .05.
§ Significantly different from the correspondent control side at α level of .01.