Table 1:

Statistics for quantitative hippocampal MR imaging data (HADC, HCVOL, HCT2, and HCSI)

HippocampusControls (n = 20)Right TLE (n = 29)Left TLE (n = 26)
ADC (mm2/s 105) (HADC)
    Right hippocampus0.87 ± 0.03 (0.83–0.93)1.03 ± 0.14 (0.83–1.34)§0.86 ± 0.05 (0.83–0.96)
    Left hippocampus0.88 ± 0.03 (0.84–0.93)0.85 ± 0.06 (0.76–1.04)1.01 ± 0.15 (0.80–1.39)§
    A.I.1.3 ± 1.2 (0.02–3.9)17.6 ± 10.8 (2.7–44.7)§15.2 ± 12.5 (0.3–38.5)§
Volume (mm3) (HCVOL)
    Right hippocampus3611 ± 350 (3050–4450)§2591 ± 587 (1449–3843)§3354 ± 399 (2251–3947)
    Left hippocampus3488 ± 320 (3077–4246)3434 ± 400 (2295–4118)2427 ± 763 (1218–3660)§
    A.I.3.8 ± 2.2 (0.8–7.5)30.9 ± 17.2 (4.1–77.8)36.1 ± 24.0 (0.2–78.7)§
T2 (ms) (HCT2)
    Right hippocampus83.1 ± 2.3 (78.7–86.3)92.8 ± 5.7 (80.8–109)§85.0 ± 4.1 (72.6–92.4)
    Left hippocampus82.6 ± 2.8 (78.1–87.0)85.3 ± 3.2 (78.9–93.2)93.2 ± 7.3 (79.8–110.3)§
    A.I.1.7 ± 1.0 (0.5–3.5)9.2 ± 5.0 (0.8–24.9)§9.6 ± 7.9 (0.6–27.7)§
NAA/(Cho + CRE) (ppm) (HCSI)
    Right hippocampus0.79 ± 0.05 (0.72–0.92)0.56 ± 0.12 (0.33–0.79)§0.64 ± 0.14 (0.46–1.03)§
    Left hippocampus0.78 ± 0.06 (0.66–0.87)0.64 ± 0.08 (0.42–0.81)§0.52 ± 0.11 (0.37–0.76)§
    A.I.3.5 ± 3.1 (0.11–11.2)16.9 ± 17.3 (1.6–62.0)§21.4 ± 12.0 (0.9–39.3)§
  • Note:—TLE indicates temporal lobe epilepsy; ADC, apparent diffusion coefficient; A.I., asymmetry index; NAA/(Cho + Cre), N-acetyl-aspartate to choline and creatine ratio, or HCSI. All values are expressed as mean ± 1 SD (range).

  • *Significantly different from the contralateral side at α level of .05.

  • Significantly different from the contralateral side at α level of .01.

  • Significantly different from the correspondent control side at α level of .05.

  • § Significantly different from the correspondent control side at α level of .01.