Table 2:

Comparison between present and previous cohorts

		Present	Previous
CD decline rate^a	Stable	−0.031	0.02
	Moderate	−0.32	−0.34
	Rapid	−1.71	−3.39
CD group size	Stable	5 (31%)	10 (20%)
	Moderate	7 (44%)	27 (55%)
	Rapid	4 (25%)	12 (25%)
EDSS^b	Stable	2.0 (1.0–6.0)	2.0 (1.5–3.5)
	Moderate	1.0 (0.0–2.5)	2.0 (0.0–6.0)
	Rapid	2.5 (2.0–3.0)	2.0 (0.0–3.5)
FS decline rate^a	Stable	−0.057	0.02
	Moderate	−0.20	−0.13
	Rapid	−1.38	−2.24
FS group size	Stable	5 (31%)	10 (20%)
	Moderate	6 (38%)	32 (65%)
	Rapid	5 (32%)	7 (14%)
EDSS^b	Stable	2.0 (1.0–6.0)	2.0 (1.5–3.5)
	Moderate	1.5 (0.0–2.5)	2.0 (0.0–6.0)
	Rapid	2.5 (2.0–3.0)	2.0 (0.0–3.5)

Note:—Group rates of WBNAA decline
^a mM/year;
^b EDSS score (range). Abbreviations: CD–clinical diagnosis, EDSS–Expanded Disability Status Score, FS–first symptom.