Biochemical characteristics and MR imaging measurements with performance ranking
GCA | Subjects, n | CRP, mg/dL | ESR | Wall, mm | Lumen, mm | Lumen/wall | MR score |
---|---|---|---|---|---|---|---|
Positive | 31 | 11.2 ± 7.1 | 76.1 ± 30.9 | 0.74 ± 0.32 | 0.65 ± 0.38 | 1.23 ± 1.1 | 2.03 ± 1.05 |
Negative | 33 | 7.05 ± 7.3 | 48.8 ± 32.3 | 0.39 ± 0.18 | 0.84 ± 0.29 | 2.63 ± 1.43 | 0.45 ± 0.56 |
P value | — | 0.033 | 0.0024 | 0.00014 | 0.036 | 0.000676 | 0.000009 |
P value ranking | — | 5 | 4 | 2 | 6 | 3 | 1 |
Note:—Various parameters for the GCA-positive and GCA-negative patient collectives. GCA indicates giant cell arteritis. The C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), wall thickness, lumen diameter, ratio of lumen and wall, and the MR mural inflammation score are presented as mean ± SD. The bottom row shows the ranking of their P values when used as a single predictor for the ACR-based diagnosis, where 1 represents the lowest P value and 6 the highest.