Demographic and clinical characteristics
| Characteristic | Normal Cognition (n = 43) | MCI (n = 19) | AD (n = 55) |
|---|---|---|---|
| Sex (M/F)a | 15/28 | 5/14 | 28/27 |
| Age (yr) | 73 (±7) | 77 (±6) | 74 (±8) |
| Education (yr) | 11 (±4) | 10 (±4) | 10 (±4) |
| MMSE | 28 (±2) | 26 (±1) | 18 (±5)b |
| WMH vol. (mL) | 6.4 (±8) | 4.7 (±8) | 6.5 (±9) |
| Atrophyc | 74.7 (±4) | 72.5 (±5) | 71.2 (±5)d |
Note:—Data are represented as mean (±SD). vol. indicates volume.
a χ2 test.
b Differs from the group with normal cognition and MCI (P < .001).
c Atrophy is defined as total parenchyma volume divided by intracranial volume. Therefore, the numbers represent the percentage of intracranial volume occupied by brain parenchyma.
d Differs from the group with normal cognition (P < .01).