Correlations of MTR measurements and cognitive status measures

	Whole Brain MTR			Localized MTR
	Mmtr	NPH	PSite	Genu	Splen	FWM	CSEM	Put	Caud	Thal
MSK	−0.64^*	−0.57^*	−0.36	−0.61^*	−0.53^*	−0.46^*	−0.38	−0.51^*	−0.39	−0.51^*
Working memory	0.03	−0.51	0.32	0.11	0.29	0.25	0.31	0.06	0.08	0.09
Verbal memory	−0.14	0.51	−0.24	−0.23	−0.01	−0.28	−0.32	−0.02	−0.33	−0.05
Visual memory	0.47	0.18	0.25	0.48^*	0.48^*	0.42	0.46^*	0.10	0.30	0.30
Visuoconstruction	0.43	−0.05	0.43	0.49^*	0.20	0.56^*	0.54^*	0.28	0.41	0.37
Psychomotor	0.11	0.27	0.07	0.24	0.19	0.04	−0.12	0.15	−0.25	0.23
Motor speed	0.40	0.46	0.11	0.24	0.54^*	0.24	0.11	0.26	0.05	0.42
Executive function	−0.26	0.14	−0.25	−0.37	−0.14	−0.26	−0.22	−0.36	−0.24	−0.16

Note:—Mmtr = mean MTR; NPH, normalized peak height; Psite, peak site; Splen, splenium; FWM, frontal white matter; CSEM, centrum semiovale; Put, putamen; Caud, caudate; Tha; thalamus.
* Significant using FDR-adjusted P value. Spearman correlation coefficients for MSK; all others, Pearson correlation coefficients.