Reproducibility of the CASL perfusion method*
| Gray matter | White matter | Global | |
|---|---|---|---|
| Region of interest size (mL) | 49 ± 11 | 27 ± 5 | 76 ± 13 |
| Quantitative (mL/100 g/min) | 8 ± 8 | 8 ± 9 | 7 ± 8 |
| % difference (% baseline) | 12 ± 7 | 29 ± 24 | 14 ± 8 |
* Root-mean-square variability measured for both quantitative CBF (mL/100 g/min) and % CBF change for 7 healthy subjects breathing room air. Comparison is between measurements acquired before oxygen inhalation and 15 minutes after the inhalation of oxygen ceased; they were separated in time by 45 minutes