Table 2:

Mean NAA/Cr, Cho/Cr, and mIns/Cr ratios obtained from the WM of healthy subjects, NAWM in MS, CDL, and EDL

VOI Site	NAA/Cr (P^* Value)	Cho/Cr (P^* Value)	mIns/Cr (P^* Value)
WM of healthy subjects	1.610	1.016	0.414
	(.704)^†	(.810)^†	(.907)^†
	(.175)^‡	(.211)^‡	(.003)^‡
	(.279)^§	(.326)^§	(.849)^§
NAWM in MS	1.560	1.033	0.411
	(.704)^*	(.810)^*	(.907)^*
	(.647)^‡	(.111)^‡	(.000)^‡
	(.845)^§	(.939)^§	(.423)^§
CDL	1.452	1.110	0.557
	(.175)^*	(.211)^*	(.003)^*
	(.647)^†	(.111)^†	(.000)^†
	(.917)^§	(.928)^§	(.097)^§
EDL	1.455	1.120	0.404
	(.279)^*	(.326)^*	(.848)^*
	(.845)^†	(.940)^†	(.423)^†
	(.917)^‡	(.928)^‡	(.097)^‡

Note:—NAA indicates N-acetylaspartate; Cr, creatine; Cho, choline; mIns, myo-inositol; WM, white matter.
* Value in comparison with the WM of healthy subjects.
† P value in comparison with the NAWM of MS.
‡ P value in comparison with CDL.
§ P value in comparison with EDL.