Structural MR imaging−derived measures from healthy volunteers and patients with PPMS
| Healthy Volunteers | PPMS | Pa | CI PPMS | CP PPMS | |
|---|---|---|---|---|---|
| Mean T2 LL (mL) | 0.98 ± 2.3 | 8.7 ± 10.7 | <.0001 | 10.5 ± 16.0 | 7.4 ± 6.1 |
| Mean NBV (mL) | 1602.1 ± 100.3 | 1528.3 ± 91.3 | .05 | 1558.7 ± 67.1 | 1505.5 ± 104.3 |
| Mean CC area (mm2) | 539.3 ± 50.5 | 508.0 ± 73.7 | n.s. | 505.5 ± 62.4 | 511.3 ± 93.1 |
a Nonparametric 2-sample t test between patients with PPMS and controls.