Table 4:

DTI measures of NAWM in pediatric MS

	Patients	Controls	P Value
Genu of CC
Mean ADC (± SD)^{^a}	0.87 (0.10)	0.82 (0.11)	.052
Mean FA (± SD)	0.53 (0.050)	0.56 (0.051)	.098
Splenium of CC
Mean ADC (± SD)^{^a}	0.91 (0.13)	0.79 (0.095)	.0010^{^b}
Mean FA (± SD)	0.58 (0.073)	0.65 (0.052)	.0003^{^b}
AMB of CC
Mean ADC (± SD)^{^a}	0.89 (0.12)	0.79 (0.085)	.0005^{^b}
Mean FA (± SD)	0.52 (0.057)	0.57 (0.051)	.0053^{^b}
PMB of CC
Mean ADC (± SD)	0.93 (0.12)	0.84 (0.11)	.011^{^b}
Mean FA (± SD)	0.53 (0.051)	0.57 (0.051)	.032^{^b}
PLIC
Mean ADC (± SD)^{^a}	0.72 (0.053)	0.71 (0.059)	.38
Mean FA (± SD)	0.56 (0.039)	0.56 (0.031)	.77
CP
Mean ADC (± SD)^{^a}	0.74 (0.061)	0.73 (0.065)	.29
Mean FA (± SD)	0.58 (0.041)	0.59 (0.044)	.18
SLF
Mean ADC (± SD)^{^a}	0.76 (0.072)	0.71 (0.070)	.0020^{^b}
Mean FA (± SD)	0.47 (0.042)	0.52 (0.043)	.00004^{^b}
IFOF and UF
Mean ADC (± SD)^{^a}	0.82 (0.081)	0.77 (0.067)	.0006^{^b}
Mean FA (± SD)	0.46 (0.038)	0.49 (0.033)	.0095^{^b}
All NAWM
Mean ADC (± SD)^{^a}	0.81 (0.062)	0.76 (0.066)	.0008^{^b}
Mean FA (± SD)	0.53 (0.033)	0.57 (0.028)	.0002^{^b}

Note:—AMB indicates anterior midbody; PMB, posterior midbody; SLF, superior longitudinal fascicle; UF, uncinate fascicle; IFOF, inferior fronto-occipital fascicle; CP, cerebral peduncle; CC, corpus callosum.
↵a ADC, × 10⁻³.
↵b Statistically significant.