Prevalence of medical conditions in patients with Williams syndrome
| Medical Condition | Study | |||
|---|---|---|---|---|
| Wint et ala (n = 14) | AAPb (n = 315) | Cherniske et alc (n = 20) | ||
| n | % | % | % | |
| Cardiovascular | 12 | 86 | 80 | 70 |
| SVAS | 9 | 64 | 75 | 65 |
| SVPS | 3 | 21 | 25 | 15 |
| Peripheral pulmonary stenosis | 1 | 7 | 50 | – |
| Mitral valve prolapse | 3 | 21 | − | 15 |
| Other | 1 | 7 | − | 35 |
| Hypertension | 4 | 29 | 50 | 60 |
| Gastrointestinal | 11 | 79 | − | 75 |
| Inguinal hernia | 5 | 36 | 40 | − |
| Constipation | 7 | 50 | 40 | 25 |
| Diverticular disease | 3 | 21 | 30 | 40 |
| Rectal prolapse | 1 | 7 | 15 | − |
| Neurologic | ||||
| Hyperreflexia | 7 | 50 | 75 | 65 |
| Gait disturbance | 11 | 79 | 60 | 70 |
| Ataxia | 10 | 71 | − | − |
| Skeletal | 6 | 43 | 50 | − |
| Spinal | 3 | 21 | 60 | 60 |
| Peripheral | 5 | 36 | 50 | 55 |
| Chronic otitis | 4 | 29 | 50 | − |
Note:—This is a comparison of the prevalence of medical problems in this study's participants with those reported in 2 large studies of Williams syndrome. The number of participants with each condition is listed in the leftmost column.
↵a Present study.
↵b American Academy of Pediatrics, 2001.32
↵c Cherniske et al, 2004.33