Demographics and clinical features
| Group | ||
|---|---|---|
| HC | ALS | |
| n | 18 | 20 |
| M/F | 10/8 | 10/10 |
| Mean age, y (SD) | 60 (10.5) | 61.5 (9.1) |
| Disease duration, mean y (SD) | n/a | 2.6 (2.7) |
| Upper limbs onset | n/a | 10 |
| Lower limbs onset | n/a | 10 |
| ALSFRS-R, mean (SD) | n/a | 36.2 (8.7) |
| 48-ALSFRS-R/months of disease duration, mean (SD) | n/a | 0.64 (0.7) |
| UMN score, mean (SD) | n/a | 7.1 (3.9) |
| FrSBe, mean (SD) | n/a | 102.3 (18.5) |
Note:—n/a indicates not applicable; SD, standard deviation.