Abnormalities in MD and FA and their association with Bayley III scores at 18–22 months corrected age in ELBW infants
Clinical/DTI Variable | Coefficient (95% CI) | P |
---|---|---|
A) Mental scale score | ||
(adjusted R2 0.34/model P 0.001) | ||
MD centrum semiovale | −45.7 (−75.6 to −15.7) | .004 |
Birth weight | 0.01 (−0.02–0.04) | .41 |
White matter injury on ultrasound | −12.5 (−23.9 to −1.0) | .03 |
Abnormal MRI findings at term | −5.0 (−14.9–4.8) | .31 |
B) Language scale score | ||
(adjusted R2 0.37/model P 0.001) | ||
MD centrum semiovale | −46.4 (−80.1 to −12.8) | .01 |
Birth weight | 0.02 (−0.02–0.054) | .28 |
White matter injury on ultrasound | −12.0 (−24.9–1.0) | .07 |
Abnormal MRI at term | −10.5 (−21.7–0.7) | .07 |
C) Cognitive scale score | ||
(adjusted R2 0.30/model P 0.003) | ||
FA subventricular zone | 244.6 (96.1–393.1) | .002 |
Birth weight | 0.01 (−0.02–0.05) | .40 |
White matter injury on ultrasound | −14.0 (−25.5 to −2.6) | .02 |
Abnormal findings on MRI at term | −5.5 (−15.6–4.6) | .28 |