Table 1:

Clinical information of the enrolled patients

VariableTrue Progression (n = 15)Pseudoprogression (n = 22)P Valuea
Age, yr (mean ± SD)59.6 ± 11.956.7 ± 13.7.61
Gender.12
    Male9 (60.0%)17 (77.3%)
    Female6 (40.0%)5 (22.7%)
Surgery.24
    Biopsy4 (26.7%)2 (9.1%)
    Subtotal6 (40.0%)9 (40.9%)
    Total5 (33.3%)11 (50.0%)
Time interval of end of TMZ-chemoradiation to DCE MRI, d (mean ± SD [range])27.0 ± 7.3 [15–44]28.7 ± 6.0 [17–44].39
End of adjuvant TMZ chemotherapy to follow-up MRI, d (mean ± SD [range])31.2 ± 10.6 [20–53]b26.2 ± 8.7 [16–54].46
Initial operation to the last follow-up, d (mean ± SD [range])391.4 ± 156.3 [224–716]657.3374.7 [274–1774].002
  • a P values are from either Student t test or the χ2 test, as appropriate, for all variables.

  • b Four patients who underwent pathologic confirmation (n = 2) or developed obvious clinical deterioration before the termination of adjuvant TMZ chemotherapy (n = 2) were excluded for this parameter.