ROC curve analysis of the discriminative power of morphometric measurements in patients with PSP, MSA, and CBD compared with all other groups
| AUC (SD) | P Value | Cutoff Value | Sensitivity (%) | Specificity (%) | Likelihood Ratio | |
|---|---|---|---|---|---|---|
| PSP vs all groups | ||||||
| Midbrain | 0.94 (0.03) | <.001 | ≤107 | 79 | 97 | 24.54 |
| Midbrain/pons | 0.93 (0.03) | <.001 | ≤0.22 | 88 | 84 | 5.42 |
| Midbrain/CC | 0.92 (0.04) | <.001 | ≤0.21 | 92 | 80 | 4.58 |
| MRPI | 0.98 (0.01) | <.001 | >12.6 | 91 | 95 | 18.48 |
| MSA (total) vs all groups | ||||||
| Pons | 0.74 (0.08) | .001 | ≤475 | 63 | 85 | 4.23 |
| Midbrain/pons | 0.86 (0.05) | <.001 | ≥0.29 | 74 | 90 | 7.05 |
| MRPI | 0.91 (0.04) | <.001 | ≤7.32 | 74 | 94 | 11.78 |
| CBD vs all groups | ||||||
| Corpus callosum | 0.79 (0.09) | .004 | ≤470 | 67 | 95 | 12.33 |
| CCP-A grad | 0.83 (0.10) | .002 | ≤191 | 75 | 97 | 25.12 |
| Pons/CCP-A grad | 0.81 (0.08) | .003 | ≥2.22 | 89 | 71 | 2.98 |
Note:—AUC indicates area under the curve.