Number, size, and location of spinal cord lesions for rater 1 and assessment of spinal cord morphologic featuresa
Quantitative Analyses | NMOSD (n = 57) | MS (n = 55) | P Valuec | Accuracy | κ Value |
---|---|---|---|---|---|
Total No. of lesions | 86 | 102 | |||
Per patient | 1 (1–2, 0–6) | 1 (0–3, 0–6) | .77 | ||
Longitudinal length (mm) | 47 (17–109, 4.5–408) | 13 (9.0–20, 4.0–208) | <.001 | ||
In cervical region (mm) | 23 (9.5–36, 4.5–149) | 13 (8.4–21, 4.0–110) | .077 | ||
In thoracic region (mm) | 63 (25–131, 6.0–408) | 13 (9.4–20, 4.1–208) | <.001 | ||
Transverse diameter (mm) | 4.4 (3.2–6.2, 1.8–13) | 4.4 (3.6–5.3, 1.9–11) | .99 | ||
In cervical region (mm) | 5.8 (3.6–7.5, 1.9–13) | 4.7 (4.0–5.8, 1.9–11) | .55 | ||
In thoracic region (mm) | 4.2 (3.1–5.7, 1.8–10) | 4.0 (3.5–4.8, 2.3–7.3) | .76 | ||
Intramedullary locationb | |||||
Central | 66 (76.7) | 59 (57.8) | .007d | ||
Peripheral | 11 (12.8) | 32 (31.4) | |||
Both | 9 (10.5) | 11 (10.8) | |||
Morphologic assessment | |||||
Atrophyb | 17 (29.8) | 5 (9.1) | .008d | 0.40 | 0.53 |
Swellingb | 19 (33.3) | 8 (14.5) | .027d | 0.41 | 0.67 |