Table 2:

Diagnostic accuracy of quantitative and qualitative (visual) assessments

	Sensitivity	Specificity	PPV	NPV	AUC (95% CI)	Diagnostic Accuracy	Cutoff
Quantitative measurements
3T NM signal	0.88	0.8	0.88	0.8	0.88 (0.79–0.97)	0.86	110.35
Volume	1	0.72	0.86	1	0.86 (0.76–0.95)	0.89	200.02
7T T2*WI volume	0.65	0.72	0.82	0.54	0.69 (0.53–0.84)	0.68	498.70
Diffusion measures
FA 3T NM	0.75	0.53	0.75	0.55	0.68 (0.54–0.82)	0.68	0.33
3T T2WI	0.65	0.70	0.8	0.52	0.64 (0.5–0.79)	0.66	0.37
AD 3T NM	0.7	0.65	0.78	0.54	0.73 (0.59–0.87)	0.68	0.64
3T T2WI	0.61	0.75	0.81	0.52	0.65 (0.49–0.80)	0.66	0.5
RD 3T NM	0.64	0.75	0.82	0.54	0.72 (0.58–0.86)	0.67	0.43
3T T2WI	0.72	0.6	0.76	0.55	0.68 (0.52–0.83)	0.67	0.29
MD 3T NM	0.67	0.75	0.83	0.56	0.72 (0.58–0.87)	0.7	0.51
3T T2WI	0.64	0.75	0.82	0.54	0.67 (0.53–0.82)	0.67	0.38
Combined measurements
NM signal and volume + FA (3T NM)	0.92	0.95	0.97	0.86	0.96 (0.9–1)	0.93	4.4
Qualitative evaluation
NM at 3T	0.83	0.9	0.94	0.9	–	0.86	–
DNH at 7T
Method 1	0.97	0.8	0.9	0.94	–	0.91	–
Method 2	0.94	0.85	0.92	0.9	–	0.91	–

Note:—AUC indicates area under the curve; NPV, negative predictive value; PPV, positive predictive value.