Patient cohorts with corresponding diagnosis as identified by an expert neuropathologist on postsurgical specimens

Site No., Initial DiagnosisCategoryPercentage CRN/Tumor as Identified by ExpertNo. of Cases
Site 1
    Primary tumorsPredominant tumor<20% CRN, >80% tumor12
Predominant CRN>80% CRN, <20% tumor10
    Metastatic tumorsPredominant tumor<20% CRN, >80% tumor12
Predominant CRN>80% CRN, <20% tumor8
Site 2
    Primary tumorsPredominant tumor<20% CRN, >80% tumor4
Predominant CRN>80% CRN, <20% tumor1
Mixed30% CRN, >70% tumor2
    Metastatic tumorsPredominant tumor<20% CRN, >80% tumor1
Predominant CRN>80% CRN, <20% tumor1
Mixed50% CRN, 50% tumor1 (50%)
Site 3
    NPCPure100% CRN13
TCIA
    GlioblastomaPure100% Tumor10

  • Note:—NPC indicates nasopharyngeal carcinoma.