Table 1:

Demographics of patients with sporadic, brain CMs (n = 51)

Clinical Information
Sex31 (60.8%) male
Age at diagnosis (yr)Median, 38.3 (range, 17.7–70.5)
Race45 (90.0%) Caucasian
Clinical presentation (No.) (%)Focal neurologic deficit, 37 (72.6%)
Seizure, 4 (7.8%)
Headache, 8 (15.6%)
Spell, not seizure, 1 (2.0%)
Other, 1 (2.0%)
Initial MRI scan brain (No.)
    Symptom onset to first MRI (day)Median, 4 (range, 0–30)
    >1 CMa3 (5.88%)
    Size (mm)Median, 12.7 (range, 4.7–34.7)
    Brain stem location31 (60.8%)
    LocationCortical, 12 (23.5%)
Supratentorial, subcortical, 6 (11.8%)
Posterior fossa, 32 (62.7%)
Intraventricular, 1 (2.0%)
    Zabramski lesion typeType I, 48 (94.2%)
Type II, 3 (5.8%)
    DVA21/42b (50.0%)
    T1 hyperintensity48 (94.1%)
    Enhancement with Gd7/42b (16.7%)
    Edema39 (76.5%)
    DWI intensityLow, 26/49b (53.1%)
Mixed, 21/49b (42.9%)
High, 2/49b (4.0%)
    ADC map intensityLow, 19/42b (45.2%)
Mixed, 23/42b (54.8%)
High, 0
    Perilesional high T1 signal17/51 (33.3%)

  • ↵a These patients had multiple CMs bordering a DVA; thus, they were considered sporadic lesions.

  • ↵b Nine patients did not have gadolinium sequences, 3 did not have DWI, and 9 did not have ADC imaging.