Comparison of baseline demographics, presentations, procedural efficacy, and safety between the GUARD and standard thrombectomy techniques
| GUARD (n = 45) | Standard (n = 45) | P Value | |
|---|---|---|---|
| Sex (% male) | 42 | 51 | .53 |
| Median age (range/yr) | 69 (21–92) | 74 (39–92) | .09 |
| Median NIHSS score (range) | 17 (6–30) | 17 (5–32) | .68 |
| Median CT ASPECTS (range) | 9 (6–10) | 9 (6–10) | .89 |
| CTP (%) | 44 | 56 | .40 |
| IV rtPA (%) | 36 | 49 | .29 |
| Vessel occlusion (%) | .88 | ||
| ICA terminus | 25 | 22 | |
| Cervical ICA + MCA | 4 | 7 | |
| MCA (M1–M2) | 71 | 71 | |
| Risk factors (%) | |||
| AF | 44 | 53 | .53 |
| HTN | 76 | 80 | .80 |
| DM | 20 | 27 | .62 |
| Smoker | 9 | 9 | .99 |
| HLD | 49 | 49 | .99 |
| Previous stroke/TIA | 7 | 11 | .71 |
| Median symptom onset-to-groin puncture time (range/min) | 192 (78–1193) | 219 (27–1097) | .241 |
| Median symptom onset to reperfusion time (range/min) | 254 (107–1245) | 279 (108–1226) | .21 |
| Median groin puncture to reperfusion time (range/min) | 52 (29–225) | 61 (23–184) | .20 |
| Mean No. of passes ± SD | 2.3 ± 1.3 | 2.8 ± 1.5 | .09 |
| First-pass reperfusion (%) | 39 | 23 | .17 |
| Final mTICI score (%) | .046a | ||
| 3 | 51 | 40 | |
| 2c | 16 | 7 | |
| 2b | 31 | 33 | |
| 2a | 2 | 16 | |
| 1 | 0 | 2 | |
| 0 | 0 | 2 | |
| Successful reperfusion mTICI ≥ 2b (%) | 98 | 80 | .015a |
| Complete reperfusion mTICI 2c/3 (%) | 67 | 47 | .09 |
| mTICI 3 (%) | 51 | 40 | .40 |
| Adjunctive stenting/angioplasty (%) | 20 | 11 | .26 |
| SICH (%) | 2 | 9 | .36 |
| Neurovascular complications (%) | 4 | 9 | .68 |
| Median mRS at 90 days (range) | 2 (0–6) | 4 (0–6) | .01a |
| mRS ≤ 2 at 90 days (%) | 67 | 43 | .04a |
| Mortality at 90 days (%) | 13 | 30 | .10 |
Note:—AF indicates atrial fibrillation; HTN, hypertension; DM, diabetes mellitus; HLD, hyperlipidemia.
↵a Significant.