Characteristics of prenatal opioid-exposed and healthy term control study cohorts

	WMI (n = 8)	No WMI (n = 12)	Control (n = 20)
Gestational age at birth (weeks)^{^a}	38.9 (0.74)	38.9 (0.93)	39.0 (0.80)
Day of life at scan^{^a}	40.6 (9.5)	43.0 (8.5)	39.3 (6.1)
Birth weight (g)^{^a}	3172 (302)	2982 (321)	3201 (460)
Birth head circumference (cm)^{^a}	34.4 (1.2)	33.9 (1.4)	34.0 (1.5)
Mom methadone^{^b}	4 (50%)	4 (33%)	0 (0%)
Mom buprenorphine^{^b}	4 (50%)	8 (67%)	0 (0%)
Mom street drugs^{^b}	3 (38%)	3 (25%)	0 (0%)
Mom alcohol^{^b}	0 (0%)	0 (0%)	0 (0%)
Mom smoking^{^b}	8 (100%)	11 (92%)	0 (0%)
Mom hepatitis C^{^b}	7 (88%)	9 (75%)	0 (0%)
Baby treated for NAS^{^b}	5 (63%)	7 (58%)	0 (0%)

Note:—NAS indicates neonatal abstinence syndrome; WMI, WM injury; Mom, mother.
↵a Values are mean (SD).
↵b Values are No. (%).