Conditions that occasionally coexist with spontaneous intracranial hypotension
| Coexisting Condition | Pathogenesis |
|---|---|
| Cerebral venous sinus thrombosis | Compensatory venous engorgement and stasis secondary to decrease in intracranial CSF volume |
| Frontotemporal dementia | Brain sag, obstruction of venous outflow, and swelling of the diencephalon may precipitate behavior and personality changes |
| Pituitary enlargement or apoplexy | Compensatory enlargement and congestion of hypophyseal veins may cause pituitary engorgement and predisposition to apoplexy |
| POTS | Prolonged supine deconditioning secondary to spinal CSF leak |
| Superficial siderosis | Venous traction at the skull base may cause microhemorrhages, or bleeding may occur at the site of the dural defect |