Table 2:

Multivariable linear mixed-effects modeling of CBF based on clinical, demographic, and study factorsa

Mod_BaselineMod_HCPMod_HCPCMS
(Intercept)43.3 (3.86)b48.4 (4.06)b50.1 (4.70)b
Postop time point6.21 (2.00)c3.01 (2.08)1.55 (2.20)
Follow-up time point14.8 (2.07)b10.5 (2.15)b7.74 (2.31)b
Age−0.686 (0.45)−1.17 (0.53)d−1.34 (0.59)d
Thalamus−5.55 (1.60)b−5.59 (1.51)b−5.60 (1.45)b
Cerebellum−10.0 (1.59)b−10.0 (1.50)b–10.0 (1.44)b
Unsedated (vs GA)3.57 (3.79)5.73 (3.93)
Hydrocephalus−19.4 (6.04)c−20.5 (6.27)c
Postop time point + HCP21.5 (5.17)b24.0 (5.13)b
Follow-up time point + HCP26.0 (5.22)b27.2 (5.18)b
CMS−10.9 (6.46)e
Postop time point + CMS8.74 (5.26)e
Follow-up time point + CMS15.6 (5.28)c
AIC1841.51824.71821.8
Marginal R20.2240.2900.295
Conditional R20.6070.6500.692
  • Note:—– indicates not included in model; GA, general anesthesia; Post-op, postoperative.

  • a Values are coefficients (standard error).

  • b P < .001.

  • c P < .01.

  • d P < .05.

  • e P < .1.