Modified diagnostic criteria in addition to the criteria of Black et al6 for SMART syndrome
| Criteria |
|---|
| A) Remote history of external beam cranial irradiation. |
| B) Prolonged signs and symptoms, which may be reversible or persistent, attributable to a unilateral cortical region. |
|  Clinical manifestations may include migraine-type headache with or without an aura, seizures, confusion, and stroke-like symptoms, including visuospatial deficits, hemisensory deficits, hemiparesis, and aphasia. |
| C) Reversible or sustained unilateral gyriform enhancement with or without T2WI/FLAIR hyperintensity involving the cortex and subjacent cerebral white matter in the irradiated area. |
| D) No definitive evidence of residual or recurrent brain tumor, and not attributable to other disorders. |