Table 2:

Subgroup comparisons between treatment groups in longitudinal ΔMCS

Default Mode NetworkASLN
Standard GroupIntensive GroupEffect Size (Cohen d)tP ValueEffect Size (Cohen d)tP Value
Overall180226–0.12–1.17.24–0.24–2.46.014a
Subgroups
 High baseline WMH94108–0.14–0.97.33–0.28–2.03.044b
 Low baseline WMH85118–0.09–0.66.51–0.21–1.47.144
 High ΔWMH10196–0.08–0.55.59–0.24–1.67.097
 Low ΔWMH77127–0.12–0.86.39–0.27–1.86.064
 Older age97131–0.12–0.90.37–0.28–2.10.037b
 Younger age8395–0.11–0.73.47–0.19–.28.20
 Larger rTBV decline87117–0.32–2.27.024b–0.09–0.64.52
 Smaller rTBV decline931090.090.66.51–0.39–2.79.0058b
  • a P <. 05, Bonferroni-corrected.

  • b P <. 05, uncorrected.