Baseline characteristics of study population
| Overall | IA Urokinase - | IA Urokinase + | P | Missing (%) | |
|---|---|---|---|---|---|
| No. | 459 | 419 | 40 | ||
| Age (median) (IQR) (yr) | 74 (63–81) | 74 (63–81) | 68 (60–76) | .02 | 0 |
| Sex male (%) | 237 (51.6) | 211 (50.4) | 26 (65.0) | .109 | 0 |
| AFib = yes (%) | 151 (32.9) | 141 (33.7) | 10 (25.0) | .349 | 0 |
| Hypertension = yes (%) | 317 (69.1) | 291 (69.5) | 26 (65.0) | .687 | 0 |
| ODT (median) (IQR) (h) | 3.03 (1.68–6.62) | 3.20 (1.71–7.22) | 2.42 (1.37–3.60) | .021 | |
| NIHSS on admission (median) (IQR) | 12 (7–18) | 13 (7–18) | 11 (6–16) | .07 | |
| SBP (median) (IQR) | 151 (133–171) | 151 (133–172) | 148 (131–161) | .332 | |
| DBP (median) (IQR) | 80 (70–93) | 80 (70–93) | 82 (73–89) | .539 | |
| Anticoagulants prestroke = yes (%) | 60 (13.1) | 53 (12.6) | 7 (17.5) | .533 | 0 |
| Antiplatelets prestroke = yes (%) | 125 (27.2) | 115 (27.4) | 10 (25.0) | .884 | 0 |
| ASPECTS (median) (IQR) | 8 (7–9) | 8 (6–9) | 9 (7–9) | .032 | 18.5 |
| ASITN/SIR collateral score (median) (IQR) | 2 (1–3) | 2 (1–3) | 2 (2–3) | .772 | 0 |
Note:—AFib indicates atrial fibrillation; ODT, onset-to-door time; SBP, systolic blood pressure; DBP, diastolic blood pressure; ASITN/SIR, American Society of Interventional and Therapeutic Neuroradiology/Society of Interventional Radiology.