Table 3: Diagnostic performance of each qualitative and quantitative parameter that showed a statistically significant difference for differentiating CS from SCa

Independent VariablesPrevalenceSensitivity (%)Specificity (%)Accuracy (%)PPV (%)NPV (%)AUC (95% CI)
Lesion center (mandibular condyle)CS 7/12 SC 0/3558.3100.089.4100.087.50.792 (0.611–0.972)
Destruction of the mandibular condyle (presence)CS 11/12 SC 20/3591.742.955.335.593.80.673 (0.510–0.835)
Destruction of articular eminence/glenoid fossa (absence)CS 8/12 SC 8/3566.777.174.550.087.10.719 (0.542–0.896)
Sclerosis of the articular eminence/glenoid fossa (absence)CS 10/12 SC 8/3583.377.178.755.693.10.802 (0.654–0.950)
Infiltration into the tendon of the LPM (presence)CS 12/12 SC 5/35100.085.789.470.6100.00.929 (0.855–1.000)
Calcification (absence or stippled)CS 10/12 SC 9/3583.374.376.652.692.90.729 (0.556–0.901)
Periosteal reaction (presence)CS 8/12 SC 4/3566.788.683.066.788.60.776 (0.604–0.948)
Internal enhancement (presence)CS 12/12 SC 3/12100.075.087.580.0100.00.875 (0.719–1.000)
Mean lesion size (≥ 30.5 mm)CS 10/12 SC 5/3583.385.785.166.793.80.889 (0.773–1.000)
  • a The items in parentheses correspond to the characteristics of CS, and 1 point was assigned if relevant imaging features in the parentheses were present.