Basic demographics of 180 subjects with HHT and brain VMs
| Characteristic | Summarya (%) |
|---|---|
| Age at enrollment (mean) (yr) | 34.2 (SD, 21.1) |
| Women | 111/180 (61.7%) |
| Curaçao criteria | |
| Epistaxis | 168/180 (93.3%) |
| Mucosal telangiectasias | 141/180 (78.3%) |
| Pulmonary AVMs | 91/180 (50.6%) |
| Liver VMs | 14/180 (7.8%) |
| Gastrointestinal bleeding | 9/180 (5.0%) |
| Affected first-degree relative | 135/180 (75%) |
| Genetic mutation | |
| ENG | 109/131 (83.2%) |
| ACVRL1 | 21/131 (16.0%) |
| SMAD4 | 1/131 (0.7%) |
| DSA | 116/180 (64.4%) |
| MRA | 114/180 (63.3%) |
| CTA | 5/180 (2.8%) |
| AVM | 113/180 (62.8%) |
| AVF | 16/180 (8.9%) |
| IAs | 9/180 (5%) |
↵a Summary is the number of observations with each value over the total available numbers (and the percentage) or the mean (SD) for continuous variables.