Measured ADC and FA values in comparison with age-matched normative data

Region	ADC	FA	Normal ADC	Normal FA
Occipital WM L	981 ± 69	0.28 ± 0.11	890 ± 110	0.33 ± 0.10
Occipital WM R	927 ± 59	0.10 ± 0.03	890 ± 110	0.33 ± 0.10
Frontal WM L	961 ± 30	0.33 ± 0.06	900 ± 50	0.31 ± 0.08
Frontal WM R	970 ± 45	0.25 ± 0.05	900 ± 50	0.31 ± 0.08
Centrum semiovale L	938 ± 24	0.38 ± 0.04	830 ± 40	0.39 ± 0.07
Centrum semiovale R	982 ± 48	0.24 ± 0.05	830 ± 40	0.39 ± 0.07
Parietal WM L	941 ± 74	0.32 ± 0.10	860 ± 60	0.32 ± 0.09
Parietal WM R	954 ± 49	0.09 ± 0.02	860 ± 60	0.32 ± 0.09
Caps. int. post. L	924 ± 42	0.58 ± 0.02	750 ± 40	0.63 ± 0.04
Caps. int. post. R	963 ± 52	0.47 ± 0.03	750 ± 40	0.63 ± 0.04
Splenium	998 ± 51	0.57 ± 0.06	940 ± 240	0.64 ± 0.09
WM lesion center	1845 ± 187	0.06 ± 0.02	830–900 ± 40–110	0.31–0.39 ± 0.07–0.10
WM lesion peripheral rim	490 ± 120	0.20 ± 0.06	830–900 ± 40–110	0.31–0.39 ± 0.07–0.10
WM focal lesions (mean)	480 ± 89	0.19 ± 0.05	830–900 ± 40–110	0.31–0.39 ± 0.07–0.10

Note.—ADC indicates apparent diffusion coefficient (mm²/s); FA, fractional anisotropy; WM, white matter; Caps. int. post., capsula interior posterior limb; L, left; R, right. FA values are scalar indices ranging from 0 to 1, where 0 represents maximal isotropic diffusion, as in a sphere, and 1 represents maximal anisotropic diffusion, as in the hypothetical case of a long cylinder of minimal diameter. Normative, age-matched ADC and FA values, which are paired with their SDs, were extracted from the literature.