Table 4:

Accuracy, sensitivity, specificity, NPV, and PPV of the different imaging techniques for the diagnosis of vasospasm requiring endovascular treatment

Endovascular Treatment or NotDSA Gold StandardTCD Absolute FV (cm/s)TCD EICA RatiosCTAPCT rCBV (cc × 100 g−1)PCT rCBF (cc × 100 g−1 × min−1)PCT MTT (s)PCT TTP (s)PCT MTT + CTA
Thresholds>180>6.00Presence or Absence of Severe<4.3<39.3>7.6>26.8
TN570501532549314560499561487
FP069382125610711083
FN04854283423183325
TP60126322637422735
Accuracy100.0%81.4%85.4%92.2%54.0%94.8%85.9%93.2%82.9%
Sensitivity100.0%20.0%10.0%53.3%43.3%61.7%70.0%45.0%58.3%
Specificity100.0%87.9%93.3%96.3%55.1%98.2%87.5%98.2%85.4%
NPV100.0%91.3%90.8%95.1%90.2%96.1%96.5%94.4%95.1%
PPV100.0%14.8%13.6%60.4%9.2%78.7%37.2%73.0%29.7%
  • Note:— MTT was again the parameter with the highest NPV, but with this time a threshold at 7.6 s, whereas PCT rCBF with a threshold at 39.3 cc × 100 g−1 × min−1 was the most accurate indicator for endovascular therapy. FV indicates flow velocity; EICA, extracranial to intracranial; rCBV, relative cerebral blood volume; rCBF, relative cerebral blood flow; MTT, mean transit time; TTP, time-to-peak; TP, true-positives; FP, false-positives; FN, false-negatives; TP, true-positives; NPV, negative predictive value; PPV, positive predictive value.