Sensitivity, specificity, PPV, and NPV for conventional imaging and the five qualitative and quantitative methods of PASL and ADC for distinguishing high-grade from low-grade gliomas
| CI | rTPmax | mADC | sTP | sADC | sTP and sADC | |
|---|---|---|---|---|---|---|
| Sensitivity (%) | 77.3 | 95.5 | 90.9 | 86.4 | 86.4 | 90.9 |
| Specificity (%) | 72.7 | 81.8 | 81.8 | 90.9 | 72.7 | 90.9 |
| PPV (%) | 85.0 | 91.3 | 90.9 | 95.0 | 86.4 | 95.2 |
| NPV (%) | 66.7 | 90.1 | 81.8 | 76.9 | 72.7 | 83.3 |
Note:—CI indicates conventional image; rTPmax, ratio of maximum tumor perfusion signal intensity; mADC, minimum ADC value; sTP, qualitative scoring of tumor perfusion signal intensity; sADC, qualitative scoring of ADC value; PPV, positive predictive value; NPV, negative predictive value.