Table 2:

Relationship between ADC (10⁻³ mm²/s) and WMSA*

Brain Region	WMSA on MRI			P Values
Brain Region	Normal (n = 39)	Focal (n = 59)	Extensive (n = 13)	Overall	Normal vs Focal^†	Normal vs Extensive^†	Focal vs Extensive^†
Inferior frontal
Right	1.74 (0.16)	1.75 (0.16)	1.85 (0.23)	.09	.99	.10	.15
Left	1.69 (0.14)	1.70 (0.15)	1.79 (0.19)	.09	.99	.09	.16
Inferior occipital
Right	1.64 (0.14)	1.68 (0.12)	1.69 (0.11)	.17	.26	.47	.99
Left	1.65 (0.16)	1.66 (0.17)	1.71 (0.16)	.44	.99	.60	.99
Internal capsule
Right	1.09 (0.04)	1.09 (0.04)	1.11 (0.06)	.24	.99	.52	.27
Left	1.12 (0.11)	1.13 (0.14)	1.12 (0.05)	.94	.99	.99	.99
Superior frontal
Right	1.64 (0.15)	1.71 (0.14)	1.73 (0.16)	.06	.07	.22	.99
Left	1.59 (0.15)	1.66 (0.15)	1.71 (0.19)	.06	.09	.06	.92
Sensorimotor
Right	1.41 (0.20)	1.51 (0.21)	1.65 (0.26)	.002^‡	.07	.002^‡	.10
Left	1.44 (0.18)	1.50 (0.21)	1.63 (0.18)	.009^‡	.30	.007^‡	.10
Superior occipital
Right	1.66 (0.18)	1.81 (0.15)	1.65 (0.14)	.004^‡	.99	.01^‡	.003^‡
Left	1.64 (0.17)	1.72 (0.18)	1.65 (0.18)	.39	.99	.53	.68

Note:—ADC indicates apparent diffusion coefficient; WMSA, white matter signal-intensity abnormalities.
* Values are mean (SD).
† P values after Bonferroni correction.
‡ Significant P values.