Scan-rescan group lesion volume and interscan coefficient of variation
| Methods | Baseline Lesion Volume, Mean ± SD, cm3 | Rescan Lesion Volume, Mean ± SD, cm3 | Average Interscan COV, Mean ± SD, % | Lesion Volume Change, Mean ± SD, cm3 | Percentage of Lesion Volume Change, Mean ± SD, % |
|---|---|---|---|---|---|
| CSEG | 7.98 ± 6.8* | 8.50 ± 7.66 | 8.64 ± 9.91 | 0.77 ± 1.1 | 11.40 ± 12.00 |
| SSEG | 7.98 ± 6.8* | 8.12 ± 7.08† | 0.98 ± 1.55 | 0.14 ± 0.28 | 1.50 ± 2.30 |
Note:—COV indicates coefficient of variation; CSEG, serial single time-point conventional segmentation; SSEG, segmentation of subtraction images.
* The same baseline lesion volume (calculated with CSEG) is used with the 2 methods.
† Rescan volume with SSEG = baseline volume (calculated with CSEG) + net lesion volume change (calculated with SSEG); percentage of lesion volume change = lesion volume change/baseline lesion volume.