Immunohistochemical findings in 14 eyes with retinoblastoma
Case No./Sex/Age (mo) | AES | VEGF | Flt-1 | CD31 | ||
---|---|---|---|---|---|---|
Enhancement | Iris Surface | Iris Stroma | Iris Surface | Iris Stromaa | IAb | |
1/M/2 | Normal | Strong | Weak | Weak | Weak | 1 |
2/F/25 | Normal | Weak | Negative | Negative | Negative | 0 |
3/M/4 | Normal | Strong | Weak | Weak | Weak | 0 |
4/M/12 | Normal | Negative | Negative | Negative | Negative | 0 |
5/M/31 | Normal | Strong | Weak | Negative | Weak | 0 |
6/F/26 | Moderate | Weak | Negative | Negative | Weak | 0 |
7/F/16 | Moderate | Strong | Weak | Strong | Weak | 3 |
8/F/2 | Moderate | Strong | Weak | Negative | Weak | 0 |
9/M/2 | Moderate | Strong | Strong | Negative | Weak | 0 |
10/M/36 | Strong | Weak | Negative | Negative | Weak | 1 |
11/F/20 | Strong | Negative | Negative | Negative | Weak | 2 |
12/M/29 | Strong | Weak | Negative | Negative | Weak | 3 |
13/M/6 | Strong | Strong | Weak | Strong | Strong | 2 |
14/M/3 | Strong | Strong | Weak | Negative | Weak | 1 |
a Significant correlation between AES enhancement and the data in this column (r = .555; P = .04)
b Significant correlation between AES enhancement and the data in this column (r = .665; P = .009). IA according to the Pe'er classification.12