Table 1:

Demographic and clinical features of patients with ALS and healthy controls

Healthy ControlsALS PatientsPa
N1516
Age (yr)63 ± 12 (43–77)61 ± 10 (40–74)0.47
Women (%)8 (53)8 (50)0.85
Education (yr)12 ± 6 (5–24)9 ± 4 (5–17)0.18
Disease duration (mo)29 ± 19 (3–84)
ALSFR-R score33 ± 7 (22–44)
UL-MRC score54 ± 11 (39–68)
LL-MRC score33 ± 15 (2–48)
UMN score13 ± 4 (3–16)
  • Note:—Values are means ± SD (range) or N (percentages); UL-MRC indicates Upper Limb-Medical Research Council; LL-MRC, Lower Limb-Medical Research Council.

  • a Pearson χ2 test or the Mann-Whitney U test, as appropriate.