Mean subcortical nuclei volume in cubic centimeters per diagnosis: MANCOVA analysis applied for estimating group differencesa
| Anatomy | A | B | C | MANCOVA | Post Hoc Comparison | Cohen D | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Control | Child B | Child C | ||||||||||
| Mean Volume (SD) (cm3) | F | P Value | A vs B | B vs C | A vs C | |||||||
| L accumbens | 0.39 | (0.11) | 0.35 | (0.09) | 0.30 | (0.07) | 2.64 | .08 | 0.42 | 0.69 | 1.01 | |
| L amygdala | 1.12 | (0.19) | 1.02 | (0.20) | 0.94 | (0.23) | 3.12 | .05b | A > C; A, B (NS); B, C (NS) | 0.51 | 0.39 | 0.87 |
| L caudate | 3.09 | (0.35) | 2.92 | (0.48) | 2.70 | (0.41) | 3.53 | .04b | A > C; A, B (NS); B, C (NS) | 0.39 | 0.49 | 1.01 |
| L hippocampus | 3.61 | (0.44) | 3.66 | (0.41) | 3.51 | (0.72) | 0.11 | .90 | −0.13 | 0.27 | 0.17 | |
| L pallidus | 1.78 | (0.28) | 1.60 | (0.48) | 1.57 | (0.56) | 1.21 | .31 | 0.47 | 0.04 | 0.47 | |
| L putamen | 4.77 | (0.54) | 4.33 | (0.87) | 3.81 | (0.75) | 7.17 | <.01b | A > B; A > C; B, C (NS) | 0.60 | 0.64 | 1.47 |
| L thalamus | 7.24 | (0.62) | 7.25 | (0.56) | 6.84 | (0.63) | 0.78 | .46 | −0.02 | 0.69 | 0.64 | |
| R accumbens | 0.29 | (0.09) | 0.26 | (0.12) | 0.22 | (0.09) | 1.03 | .36 | 0.30 | 0.32 | 0.71 | |
| R amygdala | 1.08 | (0.22) | 0.95 | (0.25) | 0.93 | (0.20) | 2.59 | .09 | 0.53 | 0.10 | 0.70 | |
| R caudate | 3.22 | (0.40) | 3.20 | (0.52) | 2.97 | (0.42) | 0.76 | .47 | 0.04 | 0.49 | 0.61 | |
| R hippocampus | 3.77 | (0.53) | 3.85 | (0.58) | 3.75 | (0.38) | 0.06 | .94 | −0.14 | 0.20 | 0.04 | |
| R pallidus | 1.78 | (0.30) | 1.63 | (0.44) | 1.56 | (0.46) | 1.13 | .33 | 0.38 | 0.17 | 0.57 | |
| R putamen | 4.58 | (0.51) | 4.24 | (0.81) | 3.96 | (0.73) | 3.71 | .03b | A > B; A > C; B, C (NS) | 0.51 | 0.37 | 0.99 |
| R thalamus | 6.99 | (0.61) | 7.07 | (0.54) | 6.74 | (0.70) | 0.12 | .89 | −0.14 | 0.53 | 0.38 | |