Qualitative assessment of patients with brain tumorsa
| Diagnostic Information End Point | Reader | Gadobenate Dimeglumine Preferred | Gadobutrol Preferred | Significance (P Value) | 3-Reader Agreement (κ value) |
|---|---|---|---|---|---|
| Global diagnostic preference | 1 | 46 (40.7%) | 6 (5.3%) | <.0001 | 0.524 (61.9%) |
| 2 | 54 (47.4%) | 7 (6.1%) | <.0001 | ||
| 3 | 49 (53.2%) | 7 (6.1%) | <.0001 | ||
| Lesion border delineation | 1 | 43 (38.1%) | 5 (4.4%) | <.0001 | 0.544 (66.4%) |
| 2 | 39 (34.2%) | 3 (2.6%) | <.0001 | ||
| 3 | 37 (34.0%) | 3 (2.6%) | <.0001 | ||
| Definition of disease extent | 1 | 18 (15.9%) | 1 (0.9%) | <.0001 | 0.414 (73.5%) |
| 2 | 21 (18.4%) | 3 (2.6%) | <.0001 | ||
| 3 | 20 (17.5%) | 0 | <.0001 | ||
| Visualization of lesion internal morphology | 1 | 39 (34.5%) | 5 (4.4%) | <.0001 | 0.629 (73.5%) |
| 2 | 35 (30.7%) | 4 (3.5%) | <.0001 | ||
| 3 | 36 (31.6%) | 1 (0.9%) | <.0001 | ||
| Lesion contrast enhancement | 1 | 53 (46.9%) | 7 (6.2%) | <.0001 | 0.547 (62.8%) |
| 2 | 62 (54.4%) | 10 (8.8%) | <.0001 | ||
| 3 | 50 (43.9%) | 7 (6.1%) | <.0001 |
↵a Comparisons based on 113 patients for reader 1 and 114 patients for readers 2 and 3. All other comparisons were considered equal. Numbers in parentheses represent proportions of patients.