Demographics of the patients
| Demographic | No. |
|---|---|
| Total | 75 |
| Focus laterality | |
| Right | 35 |
| Left | 40 |
| Focus location | |
| Temporal | 57 |
| Frontal | 13 |
| Parietal | 1 |
| Occipital | 2 |
| Temporo-occipital | 1 |
| Parieto-occipital | 1 |
| Histologic diagnosis | |
| MTS | 34 |
| MCD | |
| Cortical dysplasia | 8 |
| Tuberous sclerosis | 2 |
| Heterotopia | 1 |
| Tumor | |
| Glioma | 8 |
| Ganglioglioma | 3 |
| Amygdalar hamartoma | 3 |
| Angioma | 3 |
| DNT | 3 |
| Nonspecific | |
| No remarkable abnormality | 8 |
| Atrophy | 2 |
| Prognosis (Engel classification)a | |
| Ia | 44 |
| Ib | 9 |
| Ic-d | 0 |
| IIa | 0 |
| IIb | 22 |
| IIc-d | 0 |
| III | 0 |
| IV | 0 |
| Medicationb | |
| CBZ | 52 |
| PHT | 34 |
| PB | 18 |
| VPA | 11 |
| CLB | 14 |
| DZP | 1 |
| CZP | 4 |
| Application of invasive EEGc | |
| No | 52 |
| Yes | 23 |
Note:—DNT indicates dysembryoplastic neuroepithelial tumor; CBZ, carbamazepine; PHT, phenytoin; PB, phenobarbital; VPA, sodium valproate; CLB, clobazam; DZP, diazepam; CZP, clonazepam.
↵a Class I: Free of disabling seizures. a, Completely seizure-free since surgery. b, Nondisabling simple partial seizures only since surgery. c, Some disabling seizures after surgery, but free of disabling seizures for at least 2 years. d, Generalized convulsions with antiepileptic drug discontinuation only. Class II: Rare disabling seizures. (“almost seizure-free”) a, Initially free of disabling seizures but has rare seizures now. b, Rare disabling seizures since surgery. c, More than rare disabling seizures since surgery, but rare seizures for the last 2 years. d, Nocturnal seizures only. Class III: Worthwhile improvement. a, Worthwhile seizure reduction. b, Prolonged seizure-free intervals amounting to greater than half the follow-up period, but not <2 years. Class IV: No worthwhile improvement. a, Significant seizure reduction. b, No appreciable change. c, Seizures worse.
↵b Use of anticonvulsants at the time of I-123 iomazenil SPECT examination.
↵c Group of patients who underwent 2-step surgery: intracranial EEG electrode implantation and foci resection. This group comprised 5 cases of MTS, 6 cases of MCD, 7 tumors, and 5 healthy patients.