Patient demographics and clinical data
| Control Group | 6-OPRI Group | P Value | |
|---|---|---|---|
| N | 16 (8 M) | 9 (4 M) | − |
| Age (y) | 37.1 ± 10.7 | 38.1 ± 3.6 | ns |
| MMSE | 30 (30–30) | 19 (11–27) | <.001 |
| CDR | − | 8 (2–14) | .002a |
Note:—CDR indicates Clinical Dementia Rating Scale; M, male; N, number; MMSE, Mini-Mental State Examination; ns, not significant (P≥0.1); 6-OPRI, 6-octapeptide repeat insertion. Age values are mean ± SD. MMSE and CDR values are median (range).
↵a All comparisons were performed with the Mann-Whitney U test, except for CDR, for which the Wilcoxon test vs CDR = 0 was performed.