Table 3:

Linear regression analysis including diffusion tensor imaging measures, T2 lesion burden, and white matter and cortical volumes in the healthy control group

	T2-LV	NWMV	NCV
FA, Total SDGM	0.024	−0.103	−0.136
β, P value	.864	.493	.451
Caudate	0.049	0.114	−0.102
β, P value	.674	.360	.553
Thalamus	0.057	0.090	0.121
β, P value	.626	.481	.480
Hippocampusr	−0.024	−0.152	−0.063
β, P value	.862	.211	.728
MD, Total SDGM	0.154	−0.348^*	−0.318^*
β, P value	.135	.001^*	.033^*
Caudate	0.010	−0.226^*	−0.337^*
β, P value	.936	.033^*	.015^*
Thalamus	0.159	−0.325^*	−0.376^*
β, P value	.099	.001^*	.006^*
Hippocampus	0.165	−0.250^*	−0.130
β, P value	.141	.037^*	.466
AD, Total SDGM	0.152	−0.336^*	−0.321^*
β, P value	.140	.002^*	.033^*
Caudate	0.024	−0.224^*	−0.371^*
β, P value	.847	.034^*	.008^*
Thalamus	0.157	−0.313^*	−0.369^*
β, P value	.100	.002^*	.006^*
Hippocampus	0.149	−0.253^*	−0.134
β, P value	.190	.034^*	.451
RD, Total SDGM	0.157	−0.349^*	−0.315^*
β, P value	.130	.001^*	.036^*
Caudate	0.007	−0.206	−0.318
β, P value	.958	.051	.237
Thalamus	0.141	−0.329^*	−0.377^*
β, P value	.141	<.001^*	.006^*
Hippocampus	0.174	−0.244^*	−0.126
β, P value	.122	.042^*	.483

Note:—NCV indicates normalized cortical volume; NWMV, normalized white matter volume; T2-LV, T2 lesion volume.
Regression analysis was adjusted for the effects of age and sex. All P values were corrected for multiple comparisons using Benjamini-Hochberg correction.
↵* indicates significant P values (P < .05) after correction.