Table 4:

Sensitivity and specificity for the presence of multiple SWI-filtered phase signal abnormalities and fulfillment of the McDonald 2005³⁰ and 2010⁷ criteria for dissemination in space between patients with clinically isolated syndrome and other neurologic disorders^{^a}

	CIS vs. OND
	Sensitivity	Specificity	Accuracy
≥2 Phase WM-SAs	56.3	83.3	66.7^{^b}
≥3 Phase WM-SAs	43.8	90	61.5^{^c}
≥4 Phase WM-SAs	43.8	93.3	62.8^{^b}
McDonald 2005 criteria for DIS	52.1	80	62.8^{^c}
McDonald 2010 criteria for DIS	62.5	76.7	67.9^{^c}
≥2 Phase + McDonald 2005 criteria for DIS	33.3	90	55.1
≥2 Phase + McDonald 2010 criteria for DIS	39.6	90	58.9^{^c}

Note:— P < .05. P values have been corrected for false discovery rate at the P < .05 level.
↵a Sensitivity and specificity were computed using cross-tabulations.
↵b P < .001.
↵c P < .01.